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HoxB13 in prostate cancer
mis-sense change (G84E) in HOXB13 was found overall in 1.4% of prostate cancer cases and in 0.1% of unaffected controls http://www.ncbi.nlm.nih.gov/pubmed/22236224
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Mapping rare and common causal alleles for complex human diseases
Mapping rare & common causal alleles for complex human diseases: great primer, describing yin & yang of #RVAS v #GWAS http://www.cell.com/retrieve/pii/S0092867411010695 Found this a very...
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Kiezun A, Garimella K, Do R, Stitziel NO, Neale BM, McLaren PJ, Gupta N,...
#Exome sequencing & #genetic basis of complex traits http://www.nature.com/ng/journal/v44/n6/full/ng.2303.html Key pt: amt of rare variants exceeds that from neutral model Kiezun A, Garimella K, Do...
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